NucleoFill
Nucleofill® is an advanced biostimulating injectable treatment designed to improve skin quality, boost collagen production, and promote natural skin regeneration. Using highly purified polynucleotides, Nucleofill® helps restore skin firmness, elasticity, and hydration while addressing signs of ageing for a healthier, more youthful appearance.
What Is NucleoFill?
Nucleofill® is a next-generation regenerative aesthetic treatment that uses polynucleotides derived from highly purified DNA fragments to stimulate the skin's natural repair processes. Unlike traditional dermal fillers, Nucleofill® does not add volume but instead works at a cellular level to improve skin quality, increase hydration, and promote collagen and elastin production.
As the skin ages, collagen, elastin, and hydration levels decline, resulting in fine lines, skin laxity, and loss of firmness. Nucleofill® helps combat these changes by encouraging tissue regeneration and improving fibroblast activity. The treatment is commonly used on the face, neck, décolletage, and around the eyes to achieve smoother, firmer, and more radiant skin.

30-45
Min Treatment
6-12
months Duration
6-12
weeks to full effect
0
Days Downtime
Medical Disclaimer: Nucleofill is a medical procedures performed by qualified practitioners at Medaesthetix Institute. Results vary between individuals. All treatments are preceded by a thorough consultation to assess suitability. This page is for informational purposes only and does not constitute medical advice.
Why Consider Nucleofill?
Nucleofill® is an excellent treatment for individuals seeking natural skin rejuvenation without adding volume or altering facial features. By stimulating the skin's natural regenerative processes, the treatment improves overall skin quality, firmness, hydration, and elasticity while addressing the underlying causes of skin ageing.
Patients often choose Nucleofill® because it provides a holistic approach to skin rejuvenation. Rather than masking signs of ageing, it encourages the skin to repair and regenerate itself, resulting in healthier, stronger, and more youthful-looking skin that continues to improve over time.
— Key Benefits

Deep Skin Hydration
Improves moisture retention and enhances overall skin quality.

Improves Skin Firmness & Elasticity
Helps reduce skin laxity and restores a smoother, tighter appearance.

Stimulates Collagen & Elastin Production
Encourages natural tissue regeneration for firmer, more youthful skin.

Natural Skin Rejuvenation
Enhances skin health from within without adding volume or changing facial contours.
— The Process
How Nucleofill Works
Consultation
Your practitioner will assess your skin concerns, treatment goals, and suitability for Nucleofill® to create a personalised treatment plan.
Personalised Treatment Plan
A customised treatment approach is developed based on your skin condition, areas of concern, and desired outcomes.
Nucleofill® Treatment
The polynucleotide solution is carefully injected into targeted areas to stimulate cellular regeneration, collagen production, and skin revitalisation.
Results & Recovery
Following treatment, the skin gradually becomes firmer, more hydrated, and rejuvenated, with ongoing improvements visible over the following weeks and months.
— FAQ
Your Questions Answered
Everything you need to know before your first session. For anything else, our team is happy to guide you.
What is Nucleofill® used for?
Nucleofill® is used to improve skin quality, increase hydration, stimulate collagen production, enhance skin elasticity, and reduce visible signs of ageing.
Is Nucleofill® a dermal filler?
No. Nucleofill® is a regenerative biostimulator that improves skin health and quality without adding volume like traditional dermal fillers.
How many Nucleofill® treatments will I need?
Most patients benefit from a course of 2 to 3 treatments spaced several weeks apart, followed by maintenance treatments as recommended by their practitioner.
Can Nucleofill® be used around the eyes?
Who is a suitable candidate for Nucleofill®?
— Begin Your Journey
Ready to Look and Feel
Your Very Best?
Book a consultation with our medical team and discover the right Nucleofill treatment plan for your goals — aesthetic, functional, or both.

